MyBioSource.com's MOUSE ANTI RAT CD169 is a Mouse monoclonal antibody. This antibody has been shown to work in applications such as: Flow Cytometry, Immunofluorescence, Immunohistochemistry, and Immunoprecipitation.
Description
Mouse anti rat CD169 antibody, clone ED3 recognises the rat CD169 cell surface antigen, a 185kD molecule expressed by macrophages, predominately confined to lymphoid organs only. Monocytes and granulocytes are negative. No other cell types are positive. The most conspicious property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly. Furthermore, macrophages in (auto-immune) diseased tissues express the ED3 antigen. In healthy tissue no expression occurs. CD169 is a receptor for glycoconjugates containing sialic acid